Ermittlung der Viskosität von Synovialflüssigkeiten aus dem caninen Ellenbogen- und Hüftgelenk sowie dem humanen Kniegelenk

verfasst von: Gabriele Helms, Pia Rittmann, Patrick Wefstaedt, Henning Windhagen, Thomas Pressel, Bernd-Arno Behrens, Ingo Nolte
Abstract: The development of pathological changes in both human and canine hip joints is mainly caused by a lack of synovial fluid lubrication. This results in an increased joint abrasion. Even after implantation of joint prosthesis, inadequate lubrication can lead to abrasion in the tribological pair. This can finally result in aseptic loosening of the prosthesis. In spite of the enormous number of studies that have been performed on human, only little knowledge about the tribological properties of the joints in dogs is available in the literature. For this reason the viscosities of synovial fluid, derived from physiological and pathologically changed canine elbow joints were measured. The viscosities were determined by the use of a cone-plate viscometer at different temperatures and shear rates. The obtained values were compared with the viscosity values of pathologically changed synovial fluids from human knee joints as well as with pathological samples from the canine hip joint. The results show that the viscosity values vary within a series of measurements and are inversely proportional to the temperature of the sample and the shear rate. The differences between the average viscosities of canine and human synovial fluids taken from pathologically changed joints are below 4% (22.5 s(-1) at theta1 = 25 degrees C). The findings of this study are being implemented in a FE-Model for the computation of actual forces in the hip joint during different movements. This would represent a contribution to an improved prosthetic treatment of canine and human hips.
Organisationseinheit(en): Institut für Umformtechnik und Umformmaschinen
Typ: Artikel
Journal: Berliner und Munchener Tierarztliche Wochenschrift
Band: 121
Seiten: 374-80
Anzahl der Seiten: 7
ISSN: 0005-9366
Publikationsdatum: 01.10.2008
Publikationsstatus: Veröffentlicht
: Details im Forschungsportal „Research@Leibniz University“

BibTeX

@article{e4052679b7694f24bda56f652fe1a145,
title = "Ermittlung der Viskosit{\"a}t von Synovialfl{\"u}ssigkeiten aus dem caninen Ellenbogen- und H{\"u}ftgelenk sowie dem humanen Kniegelenk",
abstract = "The development of pathological changes in both human and canine hip joints is mainly caused by a lack of synovial fluid lubrication. This results in an increased joint abrasion. Even after implantation of joint prosthesis, inadequate lubrication can lead to abrasion in the tribological pair. This can finally result in aseptic loosening of the prosthesis. In spite of the enormous number of studies that have been performed on human, only little knowledge about the tribological properties of the joints in dogs is available in the literature. For this reason the viscosities of synovial fluid, derived from physiological and pathologically changed canine elbow joints were measured. The viscosities were determined by the use of a cone-plate viscometer at different temperatures and shear rates. The obtained values were compared with the viscosity values of pathologically changed synovial fluids from human knee joints as well as with pathological samples from the canine hip joint. The results show that the viscosity values vary within a series of measurements and are inversely proportional to the temperature of the sample and the shear rate. The differences between the average viscosities of canine and human synovial fluids taken from pathologically changed joints are below 4% (22.5 s(-1) at theta1 = 25 degrees C). The findings of this study are being implemented in a FE-Model for the computation of actual forces in the hip joint during different movements. This would represent a contribution to an improved prosthetic treatment of canine and human hips.",
keywords = "Animals, Dogs, Elbow Joint/pathology, Friction, Hip Joint/pathology, Hip Prosthesis, Humans, Knee Joint/pathology, Knee Prosthesis/veterinary, Lubrication, Prosthesis Design, Species Specificity, Synovial Fluid/chemistry, Temperature, Viscosity",
author = "Gabriele Helms and Pia Rittmann and Patrick Wefstaedt and Henning Windhagen and Thomas Pressel and Bernd-Arno Behrens and Ingo Nolte",
year = "2008",
month = oct,
day = "1",
language = "Deutsch",
volume = "121",
pages = "374--80",
journal = "Berliner und Munchener Tierarztliche Wochenschrift",
issn = "0005-9366",
publisher = "Schluetersche GmbH und Co",
number = "9-10",
}